what is important about the effect of clofibrate on neonatal hyperbilirubinemia?

نویسندگان

mohammad torkaman department of pediatric, school of medicine, baqiyatallah university of medical sciences, tehran, iran.

amin saburi health research center, baqiyatallah university of medical sciences, tehran, iran.

چکیده

no abstract

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Preventive Effect of Clofibrate on Neonatal Hyperbilirubinemia

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preventive effect of clofibrate on neonatal hyperbilirubinemia

background: neonatal jaundice is a common problem that can result in serious neurological side effect such as kern icterus. several drugs are used to prevent neonatal jaundice. the effect of clofibrate in the prevention of hyperbilirubi-nemia in healthy term neonates has not been paid attention to. this study aimed to evaluate the preventive effect of clofibrate on neonatal jaundice in term neo...

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The effect of clofibrate on hyperbilirubinemia of term neonates.

Clofibrate is a glucuronosyl transferase inducer that has been proposed to increase the elimination of bilirubin in neonates with hyperbilirubinemia. This study was conducted to determine the therapeutic effect of clofibrate in term neonates with non-hemolytic jaundice. This study was conducted on 52 newborns with pathologic unconjugated jaundice in Qazvin children hospital. Newborns divided ra...

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Background: Approximately 60% of term neonates and 80% of preterm ones suffer from hyperbilirubinemia in theirfirst week of life. This study sought to characterize the therapeutic effect of oral zinc sulfate on neonatalhyperbilirubinemia.Methods: In this randomized, double-blind, placebo-controlled clinical trial, 70 term neonates with total serumbilirubin (TSB) level ≥ 20 mg/dl were enrolled. ...

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Comparison of the efficacy of Clofibrate with Phenobarbital in decreasing neonatal hyperbilirubinemia

Background: Hyperbilirubinemiais a common problem in newborn infants. It can progress to kernicterus in severe forms, unless an intervention is initiated. The objective of this study was to compare the efficacy of Clofibrate with Phenobarbital in full-term neonates with nonhemolytic jaundice. Methods: this double blind clinical trial study was performed on 60 neonate who were divided randomly i...

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عنوان ژورنال:
acta medica iranica

جلد ۵۱، شماره ۲، صفحات ۱۳۹-۱۴۰

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